Three points and 11 positions separate these outfits in the Champions League table. The unpredictable nature of the table means that even though Villa are securely inside the top eight and Monaco are in the midtable pack, they could swap positions after one matchday.
Champions League football returns to the Stade Louis II, but with Monaco struggling with just one league win in six and two straight Champions League defeats things might not be straightforward. Villa on the other hand have not lost in five games and have picked up results against Juventus and Leipzig recently in the Champions League.
Predicted Line Up (4-2-3-1): Radoslaw Majecki, Mohammed Salisu, Thilo Kehrer, Kassoum Ouattara, Vanderson, Lamine Camara, Soungoutou Magassa, Maghnes Akliouche, Eliesse Ben Seghir, Aleksandr Golovin, Breel Embolo
Maghnes Akliouche has two goals in Europe this season, including the opener against Barcelona in their shock 2-1 win back in September. The Monaco academy graduate has nine goal contributions this season almost equalling his 12 contributions across the entire of last season.
Predicted Line Up (4-2-3-1): Emi Martinez, Matty Cash, Ezri Konsa, Tyrone Mings, Lucas Digne, Boubacar Kamara, Amadou Onana, Youri Tielemens, Jacob Ramsey, Morgan Rodgers, Ollie Watkins
Jhon Duran has managed to pick up three goals in six games starting just one of those games. Despite his goalscoring form this season, Ollie Watkins still manages to hold his starting spot down. Watkins himself does not have a Champions League goal to his name as of yet, but will look to change that soon.
This will be the first-ever meeting between these sides. However, Lille have won four of their last five home matches against English teams.
Monaco are historically successful against English teams, especially at home. Aston Villa showed resistance in their recent league game against Arsenal, so it looks set to be an interesting game, with a draw the most likely outcome.
For that reason, our betting experts have gone with a draw at fulltime as our best-value tip for this game.
Odds of 12/5 mean that a £10 bet has the potential to return up to £34.10 in this match.
(odds subject to change)
AS Monaco 1-1 Aston Villa
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