Sassuolo vs Lazio Predictions, Lineups & Betting Tips Predictions

Serie A

Sassuolo
Sassuolo
vs
Lazio
Lazio
0 - 2Our Prediction

Sassuolo vs Lazio Predictions

Away Win

Sassuolo 0 - 2 Lazio

2.00
Best Odds When Tipped
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Visitor Picks (1x2) for Sassuolo vs Lazio

Who will win?

1

1

Sassuolo

x

Draw

2

2

Lazio

Sassuolo vs Lazio Predictions, Lineups & Betting Tips

Serie A returns with a fascinating contest as Sassuolo host Lazio at the MAPEI Stadium on 14 September 2025, kick-off 17:00 GMT. Both sides have shared a competitive rivalry in recent years, though Lazio have often had the upper hand, including back-to-back 2-0 wins in 2023.

At Football Park, our algorithm — the same model that powers our San Lorenzo vs Velez Sarsfield predictions — has assessed over 200 performance metrics to forecast this clash. Lazio emerge as favourites, with their attacking edge and strong defensive structure giving them a higher win probability. Sassuolo’s home advantage may keep the game competitive, but the data suggests the visitors carry greater value in the betting markets.

This comprehensive preview delivers predictions, head-to-head analysis, and betting insights backed by algorithm-driven probabilities.

Sassuolo vs Lazio Predictions

Home Win Probability: 40.00%

Draw Probability: 6.70%

Away Win Probability: 53.30%

Correct Score Prediction: 0-2 Lazio

Top 2 Percentage Best Bets

Lazio Win @ 2.00 – With a 53.3% win probability, Lazio provide strong value at even-money odds.

Under 2.5 Goals @ 1.91 – The algorithm projects a tight contest, with just 2.0 expected goals and only a 25% chance of seeing 3+.

Sassuolo vs Lazio Timeline & Match Insights

Goals Forecast: Low-scoring encounter, with an expected 2.0 match goals.

First Half Outlook: 67% chance of a first-half goal, but only a 20% chance of over 1.5 before the break.

Both Teams to Score: Just 30% probability, highlighting Lazio’s defensive solidity and Sassuolo’s struggles in front of goal.

Half-Time/Full-Time Projection: Away/Away – Lazio are tipped to control from the first whistle to the last.

Sassuolo vs Lazio Matches – Head-to-Head

21 Oct 2023: Sassuolo 0-2 Lazio

15 Jan 2023: Sassuolo 0-2 Lazio

12 Dec 2021: Sassuolo 2-1 Lazio

23 May 2021: Sassuolo 2-0 Lazio

24 Nov 2019: Sassuolo 1-2 Lazio

11 Nov 2018: Sassuolo 1-1 Lazio

25 Feb 2018: Sassuolo 0-3 Lazio

Recent history tilts towards Lazio, with five wins in their last seven Serie A meetings and three clean sheets across those games.

Sassuolo vs Lazio Betting Analysis

Home Win @ 3.60 – Carrying a 40% probability, Sassuolo represent an underdog bet but with limited algorithm backing.

Away Win @ 2.00 – Fairly priced considering Lazio’s superior projection.

Draw @ 3.60 – Just a 6.7% likelihood, making it a low-value selection.

Both Teams to Score @ 1.75 – Priced short, but algorithm suggests only a 30% chance.

Over 2.5 Goals @ 1.91 – Bookies suggest a coin-flip, but the data tilts heavily against this outcome.

Best Sassuolo vs Lazio Betting Tips

Lazio Win @ 2.00 – The best value play, backed by both algorithm data and head-to-head trends.

Under 2.5 Goals @ 1.91 – Strongly aligned with expected goals data and recent low-scoring patterns in this fixture.

Match Facts

Venue: MAPEI Stadium – Città del Tricolore, Reggio Emilia

Date & Kick-off: 14 September 2025, 17:00 GMT

Correct Score Prediction: Sassuolo 0-2 Lazio

Broadcast Details: To be confirmed closer to matchday

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Benji Kosartiyer
Journalist
Louis Wheeldon

Lead Writer and Betting Strategist