Liverpool vs Atletico Madrid: Lineups, Predictions & Betting Tips Predictions

Liverpool vs Atletico Madrid: Lineups, Predictions & Betting Tips

September 17, 2025 | Anfield | UEFA Champions League | 20:00 GMT

Liverpool and Atletico Madrid face off in the first round of the UEFA Champions League league phase on Wednesday night at Anfield. Both sides had disappointing campaigns last season getting knocked out by Real Madrid and PSG respectively at the round of 16 stage and will be looking to give a much better account of themselves in Europe this season, as they both start with this tough fixture.

Key Betting Tips: Liverpool to win offers good value @ 1.62, BTTS @ 1.67

Liverpool vs Atletico Madrid Predicted Lineups

Liverpool Predicted Lineup Alisson, Frimpong, Konate, Van Dijk, Robertson, Gravenberch, Szoboszlai, Salah, Wirtz, Gakpo, Ekitike

Atletico Madrid Predicted Lineups Oblak, Llorente, Le Normand, Lenglet, Ruggeri, Simeone, Barrios, Koke, Gallagher, Griezmann, Sorloth

Current Form and Standings

Liverpool come into this Champions League fixture off the back of an unbeaten start to the season in the Premier League with four wins from their first four games, sitting top of the league table. The Reds have been prolific in front of goal so far scoring nine goals in those four games, but have also conceded four and have looked shaky at times so will have to be at their best to beat Simeone's well drilled Atletico outfit.

Having said that, Atletico have started this season poorly by their high standards. The opening to their La Liga campaign has seen them get five points from their first four games, only winning one of those. This form sees them sit in the bottom half of the table in 11th and in desperate need of a win to boost their confidence.

Liverpool vs Atletico Madrid Head-to-Head Timeline

The history of this fixture has thrown up a pretty even record. Liverpool have won three, Atletico have won three, and there has been two draws. The last time the two sides met was in the group stage of the 2021/22 season, both meetings ended in a Liverpool triumph.

Recent Head-to-Head Results

03.11.21 Liverpool 2-0 Atletico Madrid

19.10.21 Atletico Madrid 2-3 Liverpool

11.03.20 Liverpool 2-3 Atletico Madrid

18.02.20 Atletico Madrid 1-0 Liverpool

02.08.17 Atletico Madrid 1-1 Liverpool

Liverpool vs Atletico Madrid Predictions

Our advanced algorithm analyses 200 data points to generate these predictions with confidence in a Liverpool win, there is also evidence to suggest BTTS. This model factors in current form, head-to-head records, player availability, and tactical matchups.

Football Park's Best Bet Liverpool to Win @ 1.62

Key players to Watch: Liverpool vs Atletico Madrid

Mo Salah (Liverpool) It is always difficult to mention key players without including Mo Salah. The Liverpool forward hasn't had an amazing season so far in terms of performances, yet has still popped up with two goals and an assist in the opening four Premier League games. The Egyptian is always a threat even when playing poorly and Atletico will have to be at their best to stop him.

Hugo Ekitike (Liverpool) The French striker has had an excellent start to the season scoring twice and getting an assist thus far. Add on to that the added threat of Alexander Isak joining the club and coming for his place, Ekitike will be looking to show that he is the main man at Liverpool with a good performance in Europe as well.

Antoine Griezmann (Atletico Madrid) Griezmann has had a poor start to this season so far, only starting one of the four La Liga games so far. Despite this, Griezmann has shown his quality over such a long period that his ability to effect a game can't be denied. Liverpool's backline will have to be switched on if they are to prevent the Frenchman from getting involved in a big way during this game.

Pablo Barrios (Atletico Madrid) Barrios has played a full 90 in three of the four games thus far in La Liga. He has put in some decent performances too with an average rating of 7.6 in those games. If Atletico are to get a hold of the midfield and really impose themselves on the game, Barrios will be crucial to that and will be hoping to continue his good form.

Liverpool vs Atletico Madrid Match Facts

• Broadcast Details: TNT Sports 1
• Referee: Maurizio Mariani
• Stadium Information: Anfield has been Liverpool's home since there formation in 1892 and has a capacity of 61,276.