Real Betis vs Lyon Predictions, Lineups and Betting Tips

Real Betis vs Lyon Predictions, Lineups and Betting Tips

Match Details: Thursday 6th November | Estadio Benito Villamarín | UEFA Europa League League Phase | 20:00 GMT

Midweek European action intensifies in the Europa League league phase. Real Betis host Lyon in Seville for Matchday 4, with both clubs chasing momentum in a format where consistency is key. Betis, fresh off a 2-2 La Liga draw with Villarreal, seek a home boost, while Lyon aim to extend their perfect European start despite domestic wobbles.

Betis hold sixth in La Liga on 16 points from 10 games, blending resilience with flair. Lyon sit mid-table in Ligue 1 but lead the league phase with nine points.

Key Betting Tip: Real Betis to Win offers strong value @ 1.90.

Real Betis vs Lyon Predicted Lineups

Real Betis Predicted XI: Pau López; Bellerín, Pezzella, Natan, Perraud; Cardoso, Altimira; Antony, Lo Celso, Ezzalzouli; Cucho Hernández

Injuries persist: Isco (ankle, out until mid-November), Junior Firpo (muscle strain), and Aitor Ruibal (hamstring) remain sidelined. Nelson Deossa (illness) is doubtful but training. Pau López returns in goal after minor discomfort. Giovani Lo Celso dictates midfield, with Cucho Hernández (four goals this season) spearheading the attack.

Lyon Predicted XI: Perri; Maitland-Niles, Mata, Niakhate, Tagliafico; Caqueret, Matic; Mikautadze, Tolisso, Benrahma; Mikautadze

No major injuries reported, enabling coach Paulo Fonseca's preferred setup. With Rayan Cherki's June 2025 transfer to Manchester City, Lyon lean on Georgian forward Georges Mikautadze (three goals in Ligue 1) up top, flanked by Said Benrahma's creativity. Nemanja Matic anchors midfield, while Ainsley Maitland-Niles bolsters the backline.

Real Betis and Lyon Current Form and Standings

Real Betis' Europa League start: 3 games, 1 win, 2 draws (5 points), featuring a home draw and away success over Ludogorets. Last five overall: W2 D2 L1, averaging 1.8 goals scored, 1.2 conceded. Unbeaten in six La Liga home games, they're sixth domestically and eyeing playoffs.

Lyon are flawless in Europe: 3 wins from 3 (9 points), including high-octane wins over Basel and Salzburg. Last five: W3 D1 L1, scoring 2.0 goals per game, conceding 1.2. Ligue 1 form is middling (10th), but their road attack shines. Five points ahead of Betis, they're top-eight contenders.

Real Betis vs Lyon Head-to-Head Timeline

Rare meetings from 2013 Europa League groups remain tight, favoring low scores.

Recent H2H Results:

Lyon 1-0 Real Betis, 28/11/13 (UEL)
Real Betis 0-0 Lyon, 19/09/13 (UEL)

Real Betis vs Lyon Predictions

Analyzing 200+ data points; form, H2H, injuries, venue, our model predicts a 2-1 Real Betis victory. Home advantage and Pellegrini's setup counter Lyon's post-Cherki transition, with over 2.5 goals in 55% of recent outings.

Best Real Betis vs Lyon Betting Tips

Football Park’s Best Bet: Real Betis to Win @ 1.90 (1win).

(Odds are subject to change)

Real Betis vs Lyon: Key Players to Watch

Cucho Hernández (Real Betis) - Four goals in nine La Liga games; his pressing and finishing have netted in three home starts.

Georges Mikautadze (Lyon) - Stepping into Cherki's void with three Ligue 1 goals; his pace could test Betis' flanks.

Real Betis vs Lyon Match Facts

Referee: To be confirmed
Broadcast Details: TNT Sports / Paramount+
Stadium Information: Estadio Benito Villamarín seats 60,721, its raucous crowd amplifying Betis' European edge.