Liverpool vs Southampton Predictions, Lineups & Betting Tips Predictions

Liverpool vs Southampton Predictions, Lineups & Betting Tips

Premier League table-toppers Liverpool host EFL Championship strugglers Southampton on Tuesday evening in the EFL Cup. The Saints came close to upsetting the Champions both home and away in the top flight last season, having led in both games, although the Reds eventually came back to win twice.

We are predicting the same outcome here, with Liverpool to win and over 2.5 goals.

Liverpool vs Southampton Predicted Lineups

Liverpool: Mamardashvili, Gomez, Williams, Robertson, Frimpong, Endo, Jones, MacAllister, Chiesa, Danns, Ekitike

Stefan Bajcetic is the only player out injured for the Reds

Southampton: McCarthy, Stephens, Harwood-Bellis, Manning, Roerslev, Downes, Charles, Azez, Fraser, Fellows, Armstrong

Liverpool vs Southampton Recent Matches Analysis

Liverpool Last Five:

Liverpool 2-1 Everton

Liverpool 3-2 Atletico (Champions League) Burnley 0-1 Liverpool

Liverpool 1-0 Arsenal

Newcastle 2-3 Liverpool

Liverpool are yet to lose this season, despite having let 2-0 leads slip thrice, before eventually winning with a late goal.

Southampton Last Five:

Hull 3-1 Southampton

Southampton 0-0 Portsmouth

Watford 2-2 Southampton

Norwich 0-3 Southampton (EFL Cup)

Southampton 1-2 Stoke

Will Still is yet to impress at St Mary's, with the club currently sat in 19th and with just one win from their opening six league games.

Liverpool vs Southampton Head-To-Head

08 Mar 2025 // Liverpool 3-1 Southampton

28 Feb 2024 // Liverpool 3-0 Southampton

12 Nov 2022 // Liverpool 3-1 Southampton

27 Nov 2021 // Liverpool 4-0 Southampton

08 May 2021 // Liverpool 2-0 Southampton

01 Feb 2020 // Liverpool 4-0 Southampton

22 Sep 2018 // Liverpool 3-0 Southampton

18 Nov 2017 // Liverpool 3-0 Southampton

07 May 2017 // Liverpool 0-0 Southampton

25 Jan 2017 // Liverpool 0-1 Southampton

An away win aside all the way back at the beginning of 2017, Liverpool have had it virtually all their own way when taking on the Saints at Anfield - expect Tuesday to be no different.

Liverpool vs Southampton Predictions

Our advanced algorithm analyzes over 200 data points to generate these predictions with 73% confidence in a home win. The model factors in current form, head-to-head records, player availability, and tactical matchups.

Liverpool vs Southampton Best Betting Tips

Football Park's Best Tip: Liverpool to win @ 1.10 - Our team of in-house betting tipsters have predicted a Liverpool win in this fixture. Their superior form, home advantage, and head-to-head record justify confidence in this selection.

Alternative Bet: Over 2.5 goals @ 1.28 - This could be on the cards, considering Liverpool's attacking power up against Southampton's shaky backline.

Key Players To Watch: Liverpool vs Southampton

Hugo Ekitike (Liverpool) The big French forward already has four goals in six Premier League matches, and will be hungry for even more as he battles with Alexander Isak for Liverpool's number nine spot.

Tom Fellows (Southampton) is the main creator for the Saints, and will have to be on his A game if they are to get an away goal, let alone take something from the game.

Match Information

23 September 2025 // KO 20:00 UK Time

The match will be shown live on both Sky and ITV in the UK.

Anfield is the stadium, which has a capacity of 61,276.